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AFFECTIVE DISORDERS IN THE ELDERLY: DIAGNOSTIC AND RESEARCH CONSIDERATIONS
GEORGOTAS, ANASTASE
Articles
Although depressive disorders in the elderly represent a major public health concern by virtue of their high cost in human suffering, disability, and potential suicide, they have not been studied extensively, and specific criteria for diagnostic classification and optimal treatment are lacking. It seems likely that many of the affective syndromes in the elderly like senile melancholia, manic depressive illness, pseudodementia, and masked depression belong to the group of endogenous depressions, and can be identified by a constellation of clinical symptoms (endogenous or endogenomorphic profile), abnormal dexamethasone suppression test (DST) (at least 50%), and positive response to treatment with antidepressant medication. The rest are depressions reactive to psychogenic or sociogenic factors frequently presenting agitation as a dominant symptom, and finally there is a group of organic depressions due to underlying organic brain change, (i.e. senile dementia). It is possible that careful psychometric and psychiatric evaluation based on the symptom pattern, DST, and response to treatment would reveal reliable differences between pseudodementia and mild dementia and distinguish endogenomorphic from non-endogenomorphic depressions, respectively. The validity of such an approach remains to be demonstrated. Biological research in this area has provided valuable findings and should be the aim for the 1980s.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/1
http://dx.doi.org/10.1093/ageing/12.1.1
en
Copyright (C) 1983, British Geriatrics Society
oai:open-archive.highwire.org:ageing:12/1/112015-05-19HighWireOUPageing:12:1
DEMENTIA IN OLD AGE AND THE NEED FOR SERVICES
CAMPBELL, A. J.
McCOSH, L. M.
REINKEN, J.
ALLAN, B. C.
Articles
A randomly selected sample of subjects aged 65 years and over was investigated to determine the prevalence of dementia. The sample, which was stratified by age, consisted of 559 subjects living in the community and institutions. It was estimated that 7.7% of those aged 65 years and over suffered from dementia. The disorder affected both sexes equally. There was a marked increase in the prevalence with age so that in those 80 years and over the prevalence rate of dementia was found to be 19%. Those suffering from dementia were significantly more likely to be receiving institutional care than those with normal intellectual function. Those with dementia used significantly more domiciliary services than did those with normal mental function and were more likely to require additional services not already provided. There was a particular need for district nursing supervision, day care and relief admissions. The high prevalence rate of dementia in the elderly, and the high use those suffering from the disorder make of both domiciliary and institutional services, should be appreciated in the planning of services for the elderly.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/11
http://dx.doi.org/10.1093/ageing/12.1.11
en
Copyright (C) 1983, British Geriatrics Society
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CORONARY CARE IN THE ELDERLY
MacDONALD, J. B.
BAILLIE, J.
WILLIAMS, B. O.
BALLANTYNE, D.
Articles
Over a five-year period (1974–78), 2947 patients were admitted to the Coronary Care Unit, Victoria Infirmary, Glasgow, and it was confirmed that 1474 of these patients had had a myocardial infarction. Over 70% were of state pensionable age, that is women over the age of 60 years and men over 65 years. No difference was found in the incidence of successful resuscitation from primary ventricular fibrillation following acute myocardial infarction between the under-60-year-old and over-70-year-old age groups. Further, this study did not show any rise in mortality, with age, following acute myocardial infarction.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/17
http://dx.doi.org/10.1093/ageing/12.1.17
en
Copyright (C) 1983, British Geriatrics Society
oai:open-archive.highwire.org:ageing:12/1/212015-05-19HighWireOUPageing:12:1
THE SIGNIFICANCE OF CARDIAC ARRHYTHMIAS IN THE AGED
TAYLOR, I. C.
STOUT, R. W.
Articles
Twenty-four-hour ambulatory electrocardiography was performed in 25 young and 29 active elderly subjects. Sinus bradycardia and sinus arrhythmia were common in the young but uncommon in the elderly. Ventricular and supraventricular premature beats and brief runs of supraventricular tachycardia were common in the elderly but uncommon in the young. Complex ventricular arrhythmias only occurred in the elderly but brief episodes of nocturnal Wenckebach AV block were quite common in young and old alike. No significant difference in arrhythmia frequency was found between elderly subjects with heart disease and those without heart disease or between elderly subjects without symptoms and those with non-episodic symptoms such as dizziness. None of the arrhythmias in the young or elderly subjects was associated with symptoms. In follow-up at 30 months, only one elderly subject was deceased (from pneumonia) and none had suffered a stroke or heart attack. It is concluded that transient cardiac arrhythmias are commoner in the elderly than in the young. However, their long-term significance remains unknown, but it is likely that they are relatively benign.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/21
http://dx.doi.org/10.1093/ageing/12.1.21
en
Copyright (C) 1983, British Geriatrics Society
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DIGOXIN KINETICS IN THE ELDERLY
REID, J.
KENNEDY, R. D.
CAIRD, F. I.
Articles
Digoxin elimination phase kinetics have been studied in 24 hospital in-patients (mean age 79 years), six of whom showed no evidence of digoxin toxicity. The others, with suspected toxicity, have been grouped according to the nature of the drug effects observed. Renal function, digoxin elimination half-life, apparent volume of digoxin distribution, and notional body content of digoxin have been compared between the groups. Apart from two hyperthyroid patients, the volumes of distribution averaged 6.1 1/kg. Toxic patients tended to have lower creatinine clearances, longer digoxin half-lives, and higher body contents of digoxin than the nontoxic, but the highest body contents were found in those with systemic toxicity. Thyrotoxicosis increases the apparent volume of digoxin distribution in the elderly.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/29
http://dx.doi.org/10.1093/ageing/12.1.29
en
Copyright (C) 1983, British Geriatrics Society
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REALITY ORIENTATION WITH ELDERLY PATIENTS IN THE COMMUNITY: AN EMPIRICAL EVALUATION
GREENE, J. G.
TIMBURY, G. C.
SMITH, R.
GARDINER, MARIE
Articles
There is now good evidence that elderly mentally impaired patients can be re-orientated for time, place and person using the technique of reality orientation (RO). To date, all empirical trials demonstrating this have been carried out on elderly institutionalized patients. This technique however might be of greater value to those elderly dementing patients still living with relatives in the community but attending geriatric psychiatry day hospitals, where they could receive RO in a consistent and systematic way. The results of an empirical study of RO with a group of such patients is reported. These showed that day hospital patients could be effectively re-orientated and that concomitant with changes in level of orientation of the patients, there were parallel changes in the patients' behaviour at home, reported stress on relatives and in relatives' mood.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/38
http://dx.doi.org/10.1093/ageing/12.1.38
en
Copyright (C) 1983, British Geriatrics Society
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CHOLECYSTECTOMY AND COLON CANCER IN THE ELDERLY
RUNDGREN, AKE
MELLSTRÖM, DAN
Articles
The incidence of colon cancer is increasing in Sweden. This is partly due to the increase of the older segments of the population. Various risk factors, such as diet, low serum cholesterol and, more recently, cholecystectomy have been found. Earlier studies, particularly regarding cholecystectomy, were carried out on in-patients of varying ages. In this longitudinal study, a representative sample of people investigated at the ages of 70 and 75 was analysed with regard to earlier cholecystectomy. Twenty-two per cent of women and 11 % of men at the ages of 70 and 75 years were found to have had this operation. A relationship between cholecystectomy and colon cancer was found for women but not for men. The cholecystectomized women had low serum cholesterol values. The female colon cancer cases were related to a high body weight. Cholecystectomized individuals can be regarded as a special group with risk factors for colon cancer.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/44
http://dx.doi.org/10.1093/ageing/12.1.44
en
Copyright (C) 1983, British Geriatrics Society
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ELECTROPHYSIOLOGICAL INVESTIGATION OF PERIPHERAL NEUROMUSCULAR DISORDERS IN THE ELDERLY
GEORGE, JAMES
TWOMEY, J. AIDAN
Articles
The results of investigation by electroneuromyography of 100 patients, aged over 70 years, with suspected neuromuscular disorders are described. A positive diagnosis was offered in 59% of patients while 36% had normal results. The value of current electrophysiological techniques in the diagnosis and management of neuromuscular disorders in the elderly is discussed.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/50
http://dx.doi.org/10.1093/ageing/12.1.50
en
Copyright (C) 1983, British Geriatrics Society
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THE EFFECT OF AGE AND SEX ON THE RESPONSE OF ENTEROPANCREATIC POLYPEPTIDES TO ORAL GLUCOSE
McCONNELL, J. G.
ALAM, M. J.
O'HARE, M. M. T.
BUCHANAN, K. D.
STOUT, R. W.
Articles
Enteropancreatic polypeptide responses during a 50 g oral glucose tolerance test were studied in 10 young men, 10 young women, 10 elderly men and 10 elderly women. Elderly females had higher gastric inhibitory polypeptide (GIP) responses to oral glucose than elderly males. Elderly males and females had higher fasting and post-glucose human pancreatic polypeptide (HPP) levels than young males and females. N-Glucagon-like immunoreactivity (N-GLI) responses differed between the young and elderly. In the young, N-GLI levels fell after oral glucose but in the elderly they rose. Post-glucose C-glucagon-like immunoreactivity (C-GLI) responses were higher in elderly females than in young females. The significance of the higher plasma levels of GIP, N-GLI and C-GLI following oral glucose in elderly females compared to elderly males is unclear.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/54
http://dx.doi.org/10.1093/ageing/12.1.54
en
Copyright (C) 1983, British Geriatrics Society
oai:open-archive.highwire.org:ageing:12/1/632015-05-19HighWireOUPageing:12:1
PROPRIOCEPTION AND SPATIAL NEGLECT AFTER STROKE
SMITH, DOROTHY L.
AKHTAR, ANWAR J.
GARRAWAY, W. MICHAEL
Articles
Proprioception and neglect were studied in 287 patients surviving up to one week after the onset of their stroke. The presence of proprioceptive loss indicated a more extensive lesion and a larger proportion of these patients had impairment of intellectual function, motor power in the upper and lower limb, and postural function. Proprioceptive loss also had an adverse effect on the level of independence achieved by discharge, final placement, mortality and length of stay in hospital. In 87% of the survivors recovery of proprioception had occurred by eight weeks. Significant neglect was associated with high mortality and poor outcome for functional recovery.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/63
http://dx.doi.org/10.1093/ageing/12.1.63
en
Copyright (C) 1983, British Geriatrics Society
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PERSISTENCE OF HIGH PLASMA GLUCOSE, INSULIN AND CORTISOL CONCENTRATIONS IN ELDERLY PATIENTS WITH PROXIMAL FEMORAL FRACTURES
FRAYN, K. N.
STONER, H. B.
BARTON, R. N.
HEATH, D. F.
GALASKO, C. S. B.
Articles
Plasma glucose, insulin and cortisol concentrations were measured in elderly patients with femoral neck fractures. The results have been compared with those in younger injured patients as well as younger and elderly control subjects. There was a prolonged elevation of plasma glucose, insulin and cortisol concentrations after femoral neck fractures, in contrast to a rapid return to normal in younger injured patients. Comparison with the control groups suggested that this might reflect the effects of immobility rather than of age or of injury <it>per se</it>. The pattern of insulin resistance together with a high cortisol concentration could hinder recovery.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/70
http://dx.doi.org/10.1093/ageing/12.1.70
en
Copyright (C) 1983, British Geriatrics Society
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HYPONATRAEMIA IN THE ELDERLY
SUNDERAM, S. G.
MANKIKAR, G. D.
Articles
A study of hyponatraemia in the in-patients of a Geriatric Department during a 10-month period showed that 77 patients (11.3%) had plasma sodium concentrations below 130 mmol/1. Thirty-one patients (4.5%) had severe hyponatraemia of less than 125 mmol/l. Seventy-three per cent of hyponatraemias were iatrogenic caused by diuretic or intravenous fluid therapy. Hydrochlorothiazide/amiloride combination has the greatest tendency to produce hyponatraemia compared to all other diuretics (<it>P</it> <0.01). Clinical features attributable to hyponatraemia were present in 61 %. Nine patients needed hospital admission solely due to hyponatraemia. The mortality rate for hyponatraemia was twice the overall rate for the unit.
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/77
http://dx.doi.org/10.1093/ageing/12.1.77
en
Copyright (C) 1983, British Geriatrics Society
oai:open-archive.highwire.org:ageing:12/1/812015-05-19HighWireOUPageing:12:1
CIRCADIAN RHYTHM OF IMMUNOGLOBULINS IN AGED PERSONS
CASALE, G.
MARINONI, G. L
d'ANGELO, R.
NICOLA, P. de
Articles
A circadian rhythm with a high statistical probability was detected for IgA, IgG and IgM in a group of 37 aged subjects. These rhythms have a peak (acrophase) in the early afternoon, around 13h00, with variable confidence interval, which may extend between 8h30 and 17h30. The double amplitude of rhythms is approximately 15% of the mean concentration of antibodies during the day (mesor). No statistical difference was observed in mesor, amplitude or acrophase between males and females or in association with age (below or above 75 years) or in mean concentration of immunoglobulins (inside or outside the adult standard reference value at 8h00).
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/81
http://dx.doi.org/10.1093/ageing/12.1.81
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
HALL, DAVID A.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/86-a
http://dx.doi.org/10.1093/ageing/12.1.86-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
DAVISON, WILLIAM
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/86
http://dx.doi.org/10.1093/ageing/12.1.86
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
RUDD, T. N.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/87-a
http://dx.doi.org/10.1093/ageing/12.1.87-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
HALL, DAVID A.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/87-b
http://dx.doi.org/10.1093/ageing/12.1.87-b
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
ISAACS, BERNARD
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/87
http://dx.doi.org/10.1093/ageing/12.1.87
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
EVANS, J. GRIMLEY
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/88-a
http://dx.doi.org/10.1093/ageing/12.1.88-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
HALL, DAVID A.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/88
http://dx.doi.org/10.1093/ageing/12.1.88
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
WHITEHEAD, TONY
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/89-a
http://dx.doi.org/10.1093/ageing/12.1.89-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
ISAACS, BERNARD
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/89
http://dx.doi.org/10.1093/ageing/12.1.89
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
WEBSTER, S. G. P.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/90-a
http://dx.doi.org/10.1093/ageing/12.1.90-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
BOYD, R. V.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/90-b
http://dx.doi.org/10.1093/ageing/12.1.90-b
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
DAVEY, E. A.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/90-c
http://dx.doi.org/10.1093/ageing/12.1.90-c
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
WHITEHEAD, TONY
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/90
http://dx.doi.org/10.1093/ageing/12.1.90
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
EXTON-SMITH, JEAN
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/91-a
http://dx.doi.org/10.1093/ageing/12.1.91-a
en
Copyright (C) 1983, British Geriatrics Society
oai:open-archive.highwire.org:ageing:12/1/912015-05-19HighWireOUPageing:12:1
BOOK REVIEWS
WRIGHT, W. B.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/91
http://dx.doi.org/10.1093/ageing/12.1.91
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
EVANS, J. GRIMLEY
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/92-a
http://dx.doi.org/10.1093/ageing/12.1.92-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
FELSTEIN, IVOR
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/92-b
http://dx.doi.org/10.1093/ageing/12.1.92-b
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
BROCKLEHURST, J. C.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/92
http://dx.doi.org/10.1093/ageing/12.1.92
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
BOYD, R. V.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/93-a
http://dx.doi.org/10.1093/ageing/12.1.93-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
BURSTON, G. R.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/93-b
http://dx.doi.org/10.1093/ageing/12.1.93-b
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
PORTSMOUTH, O. H. D.
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/12/1/93
http://dx.doi.org/10.1093/ageing/12.1.93
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
DAVISON, WILLIAM
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/94-a
http://dx.doi.org/10.1093/ageing/12.1.94-a
en
Copyright (C) 1983, British Geriatrics Society
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BOOK REVIEWS
EVANS, J. GRIMLEY
Book Reviews
Oxford University Press
1983-01-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/12/1/94
http://dx.doi.org/10.1093/ageing/12.1.94
en
Copyright (C) 1983, British Geriatrics Society