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oai:open-archive.highwire.org:ageing:18/4/2172015-05-19HighWireOUPageing:18:4
Curing is Caring
EVANS, J. GRIMLEY
Commentary
Oxford University Press
1989-07-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/18/4/217
http://dx.doi.org/10.1093/ageing/18.4.217
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2192015-05-19HighWireOUPageing:18:4
Percutaneous Transluminal Coronary Angioplasty in Elderly Patients: A Comparison with Younger Patients
COOK, C.
HUBNER, P. J. B.
Articles
Twenty-nine patients of 287 undergoing percutaneous transluminal coronary angioplasty (PTCA) were over 65 years old. These patients, mean age 67.2 years, were compared with 258 younger patients who had a mean age of 52.6 years. The primary success rate was 76% for the older and 79% for the younger patients. The rates for vessel occlusion, myocardial infarction, emergency surgery, and restenosis were similar in the two groups. When vessel occlusion occurred, the results were more serious in the elderly and led to a fatality of 7%, compared with 0.4% for the younger patients. At 6 months' follow-up, 69% of those over 65 and 74% of those under 65 showed improvement in anginal symptoms. PTCA in older patients has similar immediate and short-term results to those in younger patients. However if complications occur, older patients have a higher fatality rate.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/18/4/219
http://dx.doi.org/10.1093/ageing/18.4.219
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2232015-05-19HighWireOUPageing:18:4
Clinical Experience with and Side-effects of Tacrine Hydrochloride in Alzheimer's Disease: A Pilot Study
FORSYTH, D. R.
SURMON, D. J.
MORGAN, R. A.
WILCOCK, G. K.
Articles
Pharmacological manipulation of central cholinergic neurotransmisson may prove beneficial in the treatment of Alzheimer's disease (AD) Tacrine hydrochloride is a central anticholinesterase which has been said to improve intellectual function in patients with AD. We report here our clinical experience with this drug in eight patients with AD, diagnosed according to DSM III and NINCDS-ADRDA criteria. Cholinergic side-effects occurred in five patients, three of whom tolerated a reduced dose. Liver function tests rose within the normal range in all patients and became abnormal in one.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/18/4/223
http://dx.doi.org/10.1093/ageing/18.4.223
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2302015-05-19HighWireOUPageing:18:4
Association of Calcaemic Status with Survival of Elderly Inpatients
SORVA, A.
TILVIS, R. S.
Articles
In 485 long-term geriatric inpatients (mean age 80 years), serum ionized calcium (Cal) concentrations were significantly associated with 2-year mortality. The cumulative 2-year survival was 37% in the hypocalcaemic group (Cal < 1.17 mmol/l), 49% in the hypercalcaemic group (Cal> 1.29 mmol/l) and 57%s in the normocalcaemic group. The association of calcaemia and survival remained significant even when patients with low serum albumin and high serum creatinine were excluded. However, serum total calcium concentrations, whether or not ‘corrected’ for albumin, were not significantly associated with survival. The use of diuretics may have had some influence on the calcaemic grouping of the patients, but the excess mortality in the hypercalcaemic group was not explained by heart failure or hypertension. The impaired survival in dyscalcaemic groups was not associated with sex, age, immobility, diabetes, hypertension, or renal failure.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/230
http://dx.doi.org/10.1093/ageing/18.4.230
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2352015-05-19HighWireOUPageing:18:4
Protein Turnover in Malnourished Elderly Subjects: The Effects of Refeeding
BEAUMONT, D.
LEHMANN, A. B.
JAMES, O. F. W.
Articles
A primed constant-rate infusion of L-(l-14C)-leucine was used to assess protein flux, synthesis, and breakdown in a group of malnourished elderly subects (n = 9) and a group of age-matched healthy elderly control subjects (n = 9). No significant differences between the two groups were observed in measures of protein metabolism. Four out of six malnourished subjects, restudied after a period of dietary replenishment, showed non-significant increases in protein synthesis and breakdown. Plasma insulin concentrations were significantly suppressed (p < 0.05) and plasma growth hormone and cortisol concentrations significantly elevated (p < 0.05) in the malnourished subjects before and after refeeding compared with the healthy elderly controls.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/235
http://dx.doi.org/10.1093/ageing/18.4.235
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2412015-05-19HighWireOUPageing:18:4
Age-associated Change in Pain Threshold Measured by Transcutaneous Neuronal Electrical Stimulation
TUCKER, M. A.
ANDREW, M. F.
OGLE, S. J.
DAVISON, J. G.
Articles
The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 health volunteers aged 5–105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain threshold may be rapidly measured by this method which is potentially of value in the assessment of patients with neurological deficits.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/241
http://dx.doi.org/10.1093/ageing/18.4.241
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2472015-05-19HighWireOUPageing:18:4
The Presentation and Management of Pituitary Tumours in the Elderly
COHEN, DAVID L.
BEVAN, JOHN S.
ADAMS, CHRISTOPHER B. T.
Articles
Twenty-two patients presenting with pituitary tumours (16 non-functioning) after the age of 70 years were identified in a review of all patients assessed in Oxford hospitals between 1982 and 1986. They were matched with younger patients, to compare modes of presentation and treatment outcome. Younger patients presented more commonly than elderly with symptoms of deficiency of adrenocorticotrophic hormone, thyroid-stimulating hormone or gonadotrophin, although the prevalence of biochemical deficiency was similar in the two groups. Trans-sphenoidal adenomectomy was performed on 12 elderly patients with visual impairment. Of those with field loss, seven improved, one was unchanged and two deteriorated after surgery, though one of the last was improved by haematoma evacuation, and two cranial nerve palsies resolved. There were no other pen-operative complications in the elderly. Transsphenoidal surgery is the treatment of choice for non-functioning turnouts causing visual failure; it decompresses the adenoma with minimal morbidity and endocrine impairment, and is well tolerated by elderly patients.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/247
http://dx.doi.org/10.1093/ageing/18.4.247
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2532015-05-19HighWireOUPageing:18:4
Geriatric Outpatient Clinics: an Audit of Clinical Action, Transport and General Practitioners' Views
DONALD, I. P.
BERMAN, P.
Articles
An audit was performed of patients attending geriatric outpatient clinics for review during a calendar month. Patients were asked to complete a brief questionnaire and 93% of case notes were available for study. In 97 attendances, management was altered in 36, a new medical problem found in 16, and 49 patients were discharged. Forty-seven attendances followed recent discharge from hospital; 19 of these patients had no evident clinical benefit from attendance, although the majority were discharged. There may be scope for a liaison nurse to take over the follow-up of some patients to save their attending a clinic. A survey of local general practitioners suggested they would welcome this.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/253
http://dx.doi.org/10.1093/ageing/18.4.253
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2582015-05-19HighWireOUPageing:18:4
Age and the Pharmacokinetics of Morphine
BAILLIE, S. P.
BATEMAN, D. N.
COATES, P. E.
WOODHOUSE, K. W.
Articles
Eight healthy young and nine healthy elderly volunteers received 10 mg morphine sulphate as an intravenous infusion, an oral solution and a slow-release tablet (MST Continus, Napp Laboratories) on three separate occasions. Pharmacokinetic profiles of morphine base were measured over a 24-h period using 13 sampling times. The elderly group showed decreased morphine clearance with a trend to a smaller volume of distribution. They achieved higher maximum plasma concentrations (C<inf>max</inf>) after both oral formulations and had larger areas under the plasma concentration-time curves. The times to reach maximum concentrations were the same in both groups for all formulations.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/258
http://dx.doi.org/10.1093/ageing/18.4.258
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2632015-05-19HighWireOUPageing:18:4
Sports Injuries in Elderly Athletes: A Three-year Prospective, Controlled Study
KANNUS, PEKKA
NIITTYMÄKI, SEPPO
JÄRVINEN, MARKKU
LEHTO, MATTI
Articles
A 3-year prospective, controlled study of sports injuries in elderly athletes (over 60 years of age) treated at an outpatient sports clinic was carried out in order to determine the number, profile, and specific features of these injuries compared with those of young athletes (between 21 and 25 years). During the study period, 57 elderly and 457 young adult athletes visited the clinic. The majority of the patients in both groups were male (83% of the veterans and 85% of the young). Forty-eight veterans (84%) were endurance sportsmen, while only 115 of the young patients (25%) went in for endurance sports. In both groups the knee joint was most frequently affected, in the young athletes (36%c) more frequently than in the elderly (21%). In the elderly athletes shoulder (18%) as well as Achilles tendon and calf (20% complaints were significantly more common than among young athletes (7% and 5%, respectively). Most (70%) of the injuries in the elderly were overuse injuries, but these comprised only 4100 in the young.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/263
http://dx.doi.org/10.1093/ageing/18.4.263
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2712015-05-19HighWireOUPageing:18:4
Multidisciplinary Assessment of Applicants for Sheltered Housing
KALRA, LALIT
FOSTER, CAROL J.
Articles
Three hundred applicants for sheltered housing underwent multidisciplinary geriatric assessment for suitability as a part of a joint assessment scheme with Local Authority Housing and Social Services Departments. Ninety-four applicants sought a move for health reasons while 206 applicants quoted housing and social reasons and denied medical problems. The assessment showed no significant disability necessitating sheltered housing facilities for 41 (44%) of the 94 people applying on health grounds. Severe disability made sheltered housing placement inappropriate for ten (10%) of the applicants with health problems. In the 206 applicants denying medical problems, the assessment revealed significant unreported physical illness in 46 (22%) and undiagnosed dementia in a further 26 (13%). Allocation of sheltered housing was affected in 99 (33%) of the 300 applicants. Eighty-two applicants were considered unsuitable, whereas 17 applicants originally thought to be unsuitable were recommended for sheltered housing. Multidisciplinary geriatric assessment is of considerable benefit in determining suitability of applicants for sheltered housing and will help in achieving better placement by avoiding inappropriate moves.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/271
http://dx.doi.org/10.1093/ageing/18.4.271
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2752015-05-19HighWireOUPageing:18:4
Footcare for Very Elderly People: A Community Survey
WHITE, E. G.
MULLEY, G. P.
Articles
We have assessed foot problems of, and chiropody provision for, 96 people aged 80 years and over who were living at home. Seventy-seven per cent had difficulty cutting their toenails and 30% complained of pain in the feet. The commonest foot problems were corns or callus, abnormal nails, hallux valgus and other toe abnormalities. Only six subjects had normal healthy feet. Of the 47 people receiving chiropody, two-thirds were being seen privately. Private chiropody tended to be performed in the home and was more frequent than National Health Service (NHS) treatment. Fifteen subjects needed but were not having chiropody. Foot problems are common in the very old. We suggest that doctors and nurses should ask old people regularly about problems cutting nails and pain in the feet. At present the provision of chiropody for old people is inadequate and ways of improving foot care must be found.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/275
http://dx.doi.org/10.1093/ageing/18.4.275
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2792015-05-19HighWireOUPageing:18:4
Hypothesis: A History of Hypothyroidism or a Family History of Pernicious Anaemia are useful in identifying Masked Pernicious Anaemia in Elderly Patients with Microcytic Hypochromic Anaemia
CATANIA, J.
CHAUDHURI, M. DATTA
SITLANI, P. K.
MANNAKKARA, J. V.
Articles
Of 2200 consecutive patients admitted to an acute geriatric unit, 58 had microcytic hypochromic anaemia. Twenty of these (34%) had serum vitamin B<inf>12</inf> below the normal range. Eleven (19%) had malabsorption of vitamin B<inf>12</inf> in eight of whom (14%) this was due to pernicious anaemia (PA). This study re-emphasizes the need for screening for PA in patients with microcytic hypochromic anaemia, particularly those with a family history or who have recognized associated diseases.
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/279
http://dx.doi.org/10.1093/ageing/18.4.279
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/282-a2015-05-19HighWireOUPageing:18:4
Ageing and the Production of Interleukin-1 by Monocytes
HORAN, M. A.
HOPKINS, S.
Letters to the Editor
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/282-a
http://dx.doi.org/10.1093/ageing/18.4.282-a
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2822015-05-19HighWireOUPageing:18:4
Cost-effectiveness of Day Care Settings for Frail Elderly People
BROCKLEHURST, J. C.
Letters to the Editor
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/282
http://dx.doi.org/10.1093/ageing/18.4.282
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2832015-05-19HighWireOUPageing:18:4
The letter above was referred to Drs Rudd and Banerjee who offer the following reply:
RUDD, A.
BANERJEE, D. K.
Letters to the Editor
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/283
http://dx.doi.org/10.1093/ageing/18.4.283
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/284-a2015-05-19HighWireOUPageing:18:4
Book Reviews
ANDERSON, FERGUSON
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/284-a
http://dx.doi.org/10.1093/ageing/18.4.284-a
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/284-b2015-05-19HighWireOUPageing:18:4
Book Reviews
JACOBY, ROBIN J.
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/284-b
http://dx.doi.org/10.1093/ageing/18.4.284-b
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2842015-05-19HighWireOUPageing:18:4
Book Reviews
WARNES, TONY
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/284
http://dx.doi.org/10.1093/ageing/18.4.284
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/285-a2015-05-19HighWireOUPageing:18:4
Book Reviews
BOYD, R. V.
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/285-a
http://dx.doi.org/10.1093/ageing/18.4.285-a
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/285-b2015-05-19HighWireOUPageing:18:4
Book Reviews
EBRAHIM, SHAH
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/285-b
http://dx.doi.org/10.1093/ageing/18.4.285-b
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2852015-05-19HighWireOUPageing:18:4
Book Reviews
JONES, ROB
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/285
http://dx.doi.org/10.1093/ageing/18.4.285
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/286-a2015-05-19HighWireOUPageing:18:4
Book Reviews
ARIE, TOM
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/286-a
http://dx.doi.org/10.1093/ageing/18.4.286-a
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/286-b2015-05-19HighWireOUPageing:18:4
Book Reviews
NEAL, CHARLES DAVID
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/286-b
http://dx.doi.org/10.1093/ageing/18.4.286-b
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2862015-05-19HighWireOUPageing:18:4
Book Reviews
CASTLEDEN, C. M.
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/286
http://dx.doi.org/10.1093/ageing/18.4.286
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/287-a2015-05-19HighWireOUPageing:18:4
Book Reviews
MIDWINTER, ERIC
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/287-a
http://dx.doi.org/10.1093/ageing/18.4.287-a
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2872015-05-19HighWireOUPageing:18:4
Book Reviews
JOLLEY, DAVID
GERMANY, ELIZABETH
Book Reviews
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/287
http://dx.doi.org/10.1093/ageing/18.4.287
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2882015-05-19HighWireOUPageing:18:4
Books Received
Books Received
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/288
http://dx.doi.org/10.1093/ageing/18.4.288
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/2761989-07-01HighWireOUPageing:18:4
Footcare for very elderly people: a community survey
White, EG
Mulley, GP
Articles
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/276
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/282a1989-07-01HighWireOUPageing:18:4
Cost-effectiveness of day care settings for frail elderly people
Brocklehurst, JC
Letters
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/282a
en
Copyright (C) 1989, British Geriatrics Society
oai:open-archive.highwire.org:ageing:18/4/282b1989-07-01HighWireOUPageing:18:4
Ageing and the production of interleukin-1 by monocytes
Horan, MA
Hopkins, S
Letters
Oxford University Press
1989-07-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/18/4/282b
en
Copyright (C) 1989, British Geriatrics Society