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oai:open-archive.highwire.org:ageing:3/4/1972015-05-19HighWireOUPageing:3:4
DEMENTIA AS AN ACCELERATED AGEING OF THE NERVOUS SYSTEM: SOME PSYCHOLOGICAL AND METHODOLOGICAL CONSIDERATIONS
MILLER, E.
Articles
Psychological evidence relevant to the hypothesis that dementia represents an accelerated ageing of the nervous system is reviewed. It is argued on methodological grounds that no definitive test of the hypothesis has yet been made. Such evidence as there is suggests that the hypothesis is inadequate as a complete explanation of dementia.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/197
http://dx.doi.org/10.1093/ageing/3.4.197
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2032015-05-19HighWireOUPageing:3:4
EPILEPSY IN THE ELDERLY
HILDICK-SMITH, MARION
Articles
Among 50 geriatric inpatients (average age 79) with late-onset epilepsy (average duration two years), 28 had grand mal attacks, 12 had focal attacks, seven had both. None had petit mal, confirming its rarity in the elderly. The epilepsy followed cerebrovascular disease (usually with hemiplegia) in 21 patients (8 per cent of all our patients with hemiplegia in the two-year study period developed epilepsy). Associated conditions included dementia in seven; and cerebral tumours (usually metastases) in five. This latter group survived less than two months on average from the onset of their attacks. The majority of patients (42 out of 50) were unfit for full neurological investigation; and the dangers of some procedures in the elderly are stressed.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/203
http://dx.doi.org/10.1093/ageing/3.4.203
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2092015-05-19HighWireOUPageing:3:4
NUTRITION OF THE ELDERLY AT HOME II. INTAKES OF VITAMINS
MACLEOD, CATRIONA C.
JUDGE, T. G.
CAIRD, F. I.
Articles
The vitamin intakes of 77 men and 187 women aged 65 and over living at home were studied using seven-day dietary records. Intakes of ascorbic acid were below 10 mg/day in 5 per cent: 25 per cent of men and 33 per cent of women took less than 50 i.u./day of vitamin D. Intakes of other vitamins (vitamin A, thiamine, riboflavin, nicotinic acid, pyridoxine, and folate) were, in general, adequate, except for small numbers of subjects. The findings are compared with those of the Panel on Nutrition of the Elderly (1972).
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/209
http://dx.doi.org/10.1093/ageing/3.4.209
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2212015-05-19HighWireOUPageing:3:4
HYPERTHYROIDISM INDUCED BY POTASSIUM IODIDE GIVEN IN THE COURSE OF 125I-FIBRINOGEN TEST
DENHAM, M. J.
HIMSWORTH, R. L.
Articles
Hyperthyroidism developed in three patients during the administration of potassium iodide given for the purpose of blocking the thyroid uptake of radioactive iodine liberated in the course of the 125I-fibrinogen test. In a consecutive series of 31 geriatric patients, who received potassium iodide for the same reason, biochemical hyperthyroidism developed in three instances and significant depression of thyroid function was observed in 10. The performance and the interpretation of the 125I-fibrinogen test are unaffected if iodide is not administered to the patient. The possible hazards to some patients of either induced hyperthyroidism or faulty assessment of thyroid function may be greater than the risk of thyroid irradiation. It is suggested that for the performance of the 125I-fibrinogen test potassium iodide need not be given to the elderly and should be given in a dose of 30 mg daily for two weeks to younger patients. Under certain circumstances potassium perchlorate may be a preferable drug for preventing the accumulation of radioactive iodine by the thyroid.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/221
http://dx.doi.org/10.1093/ageing/3.4.221
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2262015-05-19HighWireOUPageing:3:4
ACTIVE CHRONIC HEPATITIS IN THE ELDERLY
WOOLF, I. L.
BOYES, B. E.
LEEMING, J. T.
DYMOCK, I. W.
Articles
The clinical syndrome of active chronic hepatitis occurs characteristically in young people. In this report we describe three elderly patients with the syndrome. All three presented in a different manner and in two this was atypical. The diagnosis was suspected from the clinical finding of hepatomegaly or the presence of abnormal liver function tests. All three responded to treatment with corticosteroids.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/226
http://dx.doi.org/10.1093/ageing/3.4.226
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2292015-05-19HighWireOUPageing:3:4
CHANGES IN ORGAN WEIGHTS AND BLOOD PARAMETERS IN AGEING BRATTLEBORO RATS WITH HEREDITARY DIABETES INSIPIDUS
BARNETT, J. L.
CHEESEMAN, P.
CHEESEMAN, J.
DOUGLAS, J. M.
PHILLIPS, J. G.
Articles
Organ weights and blood parameters were measured in male and female Brattleboro rats with hereditary diabetes insipidus (DI) and in normal rats of the same strain, between 37 and 138 weeks old. Although differences in body weight between the homozygous DI and heterozygous normal rats accounted for differences in the weights of the heart and gonads, the weights of the spleen, liver and kidney were not solely body-weight dependent; there were significant sex and genotype differences in the mean weights of these organs. The liver, heart and gonads were the only organs showing age-dependent changes. No genotype-dependent differences were observed in the haematocrit and haemoglobin concentration, although there was a sex difference; the mean values of these parameters were higher in males. Plasma glucose concentrations were significantly lower in homozygous than in heterozygous rats; in the latter, plasma glucose concentration decreased with age. No significant changes occurred in the mean plasma concentrations of sodium or potassium with age or genotype. Total plasma lipids of heterozygous female rats showed both age- and genotype-dependent changes; this parameter reached a plateau at 90–100 weeks old, and was significantly higher in heterozygous females than in all other groups. Plasma proteins showed no age-dependent changes, but were of higher mean value in heterozygous than in homozygous rats and were greater in females than in males. Differences in blood parameters of homozygous and heterozygous Brattleboro rats are discussed in terms of differences in hormone concentrations.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/229
http://dx.doi.org/10.1093/ageing/3.4.229
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2402015-05-19HighWireOUPageing:3:4
ENDOSCOPY IN THE ELDERLY
GIBBINS, F. J.
COLLINS, HEATHER J.
HALL, R. G. P.
DELLIPIANI, A. W.
Articles
The endoscopic experience involving the study of 114 patients in the geriatric age group (65–89 years) in a district general hospital is described. The cases examined were mainly patients with dyspepsia, gastrointestinal blood loss, suspected upper alimentary tract carcinoma or those who had undergone gastric surgery. The procedure was well tolerated and safe. Useful information was obtained in the majority of patients (93 per cent). When the endoscopic and radiological findings were compared, the endoscopist and radiologist were in agreement in 55 per cent of the cases examined by both techniques. In the others, endoscopy played an essential role in establishing the presence of radiologically undetected or undetectable disease, and in confirming or excluding radiologically doubtful disease.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/240
http://dx.doi.org/10.1093/ageing/3.4.240
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2452015-05-19HighWireOUPageing:3:4
ASSESSMENT OF POTASSIUM METABOLISM, USING 42K, IN CASES OF MYXOEDEMA BEFORE AND AFTER TREATMENT WITH THYROXINE
MISRA, D. P.
STADDON, G.
POWELL, N.
JACKSON, P.
Articles
Total Exchangeable Potassium (TEK) was measured in 31 elderly patients admitted to a geriatric assessment unit. The value in control cases ranged between 26 mEq/kg to 45.5 mEq/kg; the mean values for men and women were 35.5 mEq/kg and 28.4 mEq/kg, respectively. The test was repeated after one week in eight cases, the standard deviation between the two estimations ranged from 0.35 to 1.13 with the exception of one case which was 2.55. Estimations were made in six cases of myxoedema, the initial value was low and on treatment rose by 22.6 per cent to 36.4 per cent which coincided with the clinical improvement.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/245
http://dx.doi.org/10.1093/ageing/3.4.245
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2492015-05-19HighWireOUPageing:3:4
ROUTINE SCREENING FOR VENOUS THROMBOSIS BY ULTRASOUND IN THE ELDERLY
RITCH, A. E.
EASTWOOD, H. D.
Articles
One hundred admissions to a geriatric assessment unit were screened over a three-week period with a Sonicaid Ultrasound apparatus for the development of venous thrombosis in the legs, as denoted by an abnormal ultrasound scan. Any patients with suggestive physical signs were also noted and all such patients, together with those with abnormal ultrasound findings, were investigated at the same time by the 125I-fibrinogen test. Eight patients developed an abnormal ultrasound scan confirmed with the fibrinogen method, and of these three developed abnormalities bilaterally, giving an incidence of thrombosis expressed in terms of legs of 5.5 per cent. Technical difficulties were encountered with this group of elderly patients, these being that in some there was difficulty in positioning the ultrasound probe and in others of producing an adequate flow noise to monitor changes effectively.
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/249
http://dx.doi.org/10.1093/ageing/3.4.249
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/254-a2015-05-19HighWireOUPageing:3:4
BOOK REVIEWS
HOBBS, HENRY
Book Reviews
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/254-a
http://dx.doi.org/10.1093/ageing/3.4.254-a
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2542015-05-19HighWireOUPageing:3:4
BOOK REVIEWS
MOORE-SMITH, B.
Book Reviews
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/254
http://dx.doi.org/10.1093/ageing/3.4.254
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/255-a2015-05-19HighWireOUPageing:3:4
BOOK REVIEWS
HALL, M. R. P.
Book Reviews
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/255-a
http://dx.doi.org/10.1093/ageing/3.4.255-a
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2552015-05-19HighWireOUPageing:3:4
BOOK REVIEWS
MOORE-SMITH, B.
Book Reviews
Oxford University Press
1974-11-01 00:00:00.0
TEXT
text/html
http://ageing.oxfordjournals.org/cgi/content/short/3/4/255
http://dx.doi.org/10.1093/ageing/3.4.255
en
Copyright (C) 1974, British Geriatrics Society
oai:open-archive.highwire.org:ageing:3/4/2562015-05-19HighWireOUPageing:3:4
BOOK REVIEWS
SIMS, CLIVE A.
Book Reviews
Oxford University Press
1974-11-01 00:00:00.0
TEXT
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http://ageing.oxfordjournals.org/cgi/content/short/3/4/256
http://dx.doi.org/10.1093/ageing/3.4.256
en
Copyright (C) 1974, British Geriatrics Society